Outreach

Our research agenda in 2 minutes

 

Events and activities

Happy to announce that our paper “Quantifying distribution shifts in single-cell data with scXMatch” is now out in Bioinformatics! Do cells from two conditions differ globally? In single-cell analysis, this is often judged from UMAPs, clusterings, or DEG counts, approaches that lack statistical rigor and invite confirmation bias. scXMatch answers it with a scalable, k-NN…Read more

We are excited to share that our paper “SignifiKANTE – efficient P-value computation for gene regulatory networks” has now been published in Bioinformatics. Permutation-based significance testing is a common approach for filtering edges in regression-based gene regulatory network inference, but so expensive that it is usually skipped on real-world gene expression data. We tackle this…Read more

Our GNExT paper is officially out in Nature Genetics! https://doi.org/10.1038/s41588-026-02708-6 GNExT (GWAS Network Exploration Tool) tries to make it as easy as possible to set up your own GWAS exploration platform from your GWAS summary statistics and scales well for large datasets. GNExT takes your raw GWAS dataset, preprocesses it with a custom Nextflow pipeline,…Read more

Last week, we got the happy news that our DFG-funded DyHealthNet research project will be extended by another 3 years! Our main goal in DyHealthNet is to make cohort data more explorable. In the first phase of the project, we developed prototype platforms, primarily for application to the Collaborative Health Research in South Tyrol (CHRIS)…Read more