Our GNExT paper is officially out in Nature Genetics! https://doi.org/10.1038/s41588-026-02708-6
GNExT (GWAS Network Exploration Tool) tries to make it as easy as possible to set up your own GWAS exploration platform from your GWAS summary statistics and scales well for large datasets. GNExT takes your raw GWAS dataset, preprocesses it with a custom Nextflow pipeline, and uses its output to set up a local GNExT platform instance. In GNExT, SNPs, genes, and traits can be interactively explored. We also built in tools that make it possible to mine gene subnetworks associated with a certain disease for, e.g., drug repurposing candidates.
If you have some GWAS data, we would love for you to try it out and give us some feedback at https://github.com/DyHealthNet/gnext_platform!
Congratulations to everyone involved, especially our own Fabian Woller and Lis Arend from DaiSyBio!